🔍 What is the 17-OH Ketosteroids Test?
The 17-OH Ketosteroids (17-OH KS) test measures the levels of ketosteroids in urine collected over 24 hours. These substances are byproducts of androgens (male hormones) and cortisol metabolism and help assess adrenal and gonadal function.
🎯 Purpose of the Test
Doctors may order this test to:
✅ Evaluate adrenal gland function
✅ Diagnose disorders like Cushing’s syndrome, Addison’s disease, or congenital adrenal hyperplasia (CAH)
✅ Detect abnormal androgen production (e.g., in polycystic ovary syndrome - PCOS)
✅ Investigate hormonal imbalances in both men and women
📊 Normal Ranges
Men: 7 – 20 mg/24 hrs
Women: 5 – 15 mg/24 hrs
Children: 0.3 – 3 mg/24 hrs
(Ranges may vary by lab and age group)
🔴 High 17-OH KS Levels
Causes: Cushing’s syndrome, adrenal tumors, stress, obesity
Symptoms: Weight gain, high blood pressure, irregular menstrual cycles
🟢 Low 17-OH KS Levels
Causes: Addison’s disease, adrenal insufficiency
Symptoms: Fatigue, low blood pressure, weight loss
🩺 How is the Test Done?
✅ 24-hour urine collection: Collect all urine over 24 hours in a special container.
✅ No fasting required, but avoid certain medications and foods that may interfere with results (as advised by your doctor).
📌 Consult your doctor if you have symptoms of hormonal imbalance or adrenal dysfunction!